ea0090rc9.6 | Rapid Communications 9: Adrenal and Cardiovascular Endocrinology 2 | ECE2023
Uchihara Masaki
, Tanabe Akiyo
, Umamoto Kotaro
, Maeshima Akiko Miyagi
, Kojima Yuki
, Sudo Kazuki
, Shimoi Tatsunori
, Yamazaki Yuto
, Sasano Hironobu
, Shimomura Akihiko
, Shimizu Chikako
, Yonemori Kan
, Kajio Hiroshi
Introduction: Pheochromocytoma and paraganglioma (PPGL) are rare endocrine tumors with few effective treatment options for malignant cases. Novel therapeutic indications, such as 177Lu-DOTA-TATE and immune checkpoint inhibitors (ICIs) for patients with PPGL, have been investigated in several clinical trials. Emerging evidence shows that somatostatin receptor 2 (SSTR2) in other cancer types correlates with the tumor microenvironment (TME) activation and could be a predictive bi...